Antibacterial nano cerium oxide/chitosan/cellulose acetate composite films as potential wound dressing

Kalaycıoğlu Z., Kahya N., Adımcılar V., Kaygusuz H., Torlak E., Akın-Evingür G., ...Daha Fazla

EUROPEAN POLYMER JOURNAL, cilt.133, 2020 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 133
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1016/j.eurpolymj.2020.109777
  • Dergi Adı: EUROPEAN POLYMER JOURNAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, Aerospace Database, Chimica, Communication Abstracts, Compendex, INSPEC, Metadex, Civil Engineering Abstracts
  • Anahtar Kelimeler: Nano Ceria, Wound dressing, Characterization, Antibacterial film, OXIDE, HYDROGELS, MATS
  • İstanbul Teknik Üniversitesi Adresli: Evet

Özet

Novel chitosan and cellulose acetate polymer composites with nanosized cerium oxide were prepared as potential wound dressing materials. Chitosan and cellulose acetate are natural polymer derivatives with biocompatible properties. Both polymers can be dissolved in formic acid. The polymer composite was formed by solvent-casting method. The formed films were not soluble in water. In order to improve antibacterial, thermal, and mechanical properties of the composite material, films were loaded with nanosized cerium oxide. Films were characterized with thermogravimetric, scanning electron microscopy with energy-dispersive X-ray spectroscopy, mechanical, ultraviolet-visible light transmittance, water solubility, pH, moisture content, water vapor transmission rate, swelling, and antibacterial tests. The physical properties and antibacterial characteristics of the films are promising for further research as a potential wound covering material.