FRET lasing from self-assembled DNA tetrahedral nanostructures suspended in optofluidic droplet resonators


Aas M., Ozelci E., Jonas A., Kiraz A., Liu H., Fan C., ...More

EUROPEAN PHYSICAL JOURNAL-SPECIAL TOPICS, vol.223, no.10, pp.2057-2062, 2014 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 223 Issue: 10
  • Publication Date: 2014
  • Doi Number: 10.1140/epjst/e2014-02280-1
  • Title of Journal : EUROPEAN PHYSICAL JOURNAL-SPECIAL TOPICS
  • Page Numbers: pp.2057-2062

Abstract

We demonstrate Forster resonance energy transfer (FRET) lasing from self-assembled tetrahedral DNA complexes labeled with Cy3 and Cy5 dyes and suspended as a gain medium in aqueous micro-droplet cavities deposited on a superhydrophobic surface. Threshold fluence and differential efficiency are characterized for DNA complexes containing 1Cy3-3Cy5 and 3Cy3-1Cy5. We demonstrate that at a constant Cy5 concentration, average threshold fluence is reduced 3 to 8 times and average differential efficiency is enhanced 6 to 30 times for 3Cy3-1Cy5 as compared to 1Cy3-3Cy5. Using 3Cy3-1Cy5 nanostructures, FRET lasing is observed at very low concentrations down to similar to 1 mu M. This work shows that optofluidic microlasers based on droplet resonators can be combined with DNA nanotechnology to explore applications in bio/chemical sensing and novel photonic devices.