Hamiltonian model for multidimensional epistasis


Ozcelik S., Erzan A.

INTERNATIONAL JOURNAL OF MODERN PHYSICS C, cilt.14, ss.169-173, 2003 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 14 Konu: 2
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1142/s0129183103004310
  • Dergi Adı: INTERNATIONAL JOURNAL OF MODERN PHYSICS C
  • Sayfa Sayıları: ss.169-173

Özet

We propose and solve a Hamiltonian model for multidimensional epistatic interactions between beneficial mutations. The model gives rise to either a phase transition between two equilibrium states, without any coexistence, or exhibits a state where hybrid species coexist, with gradual passage from one wild type to another. The transition takes place as a function of the tolerance of the environment, which we defined as the amount of noise in the system.