Effects of Polyvinylpyrrolidone and Ethyl Cellulose in Polyurethane Electrospun Nanofibers on Morphology and Drug Release Characteristics


Gencturk A., Kahraman E., Gungor S., Ozsoy Y., Sarac A. S.

TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, cilt.17, sa.6, ss.638-644, 2020 (ESCI İndekslerine Giren Dergi) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Konu: 6
  • Basım Tarihi: 2020
  • Doi Numarası: 10.4274/tjps.galenos.2019.87094
  • Dergi Adı: TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES
  • Sayfa Sayıları: ss.638-644

Özet

Objectives: Polyurethanes (PUs) are a popular choice for composing nanofibers due to their spinnability, biocompatibility, high chemical stability, and good mechanical and elasticity properties. The desired release behaviors are also achieved by using combinations of PUs and various polymers. In this study, we investigated effects of polyvinylpyrrolidone (PVP) and ethyl cellulose (EC) on PU electrospun nanofibers in terms of morphological structures and drug release characteristics.