Effects of Polyvinylpyrrolidone and Ethyl Cellulose in Polyurethane Electrospun Nanofibers on Morphology and Drug Release Characteristics


Gencturk A., Kahraman E., Gungor S., Ozsoy Y., Sarac A. S.

TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, vol.17, no.6, pp.638-644, 2020 (Journal Indexed in ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 6
  • Publication Date: 2020
  • Doi Number: 10.4274/tjps.galenos.2019.87094
  • Title of Journal : TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES
  • Page Numbers: pp.638-644

Abstract

Objectives: Polyurethanes (PUs) are a popular choice for composing nanofibers due to their spinnability, biocompatibility, high chemical stability, and good mechanical and elasticity properties. The desired release behaviors are also achieved by using combinations of PUs and various polymers. In this study, we investigated effects of polyvinylpyrrolidone (PVP) and ethyl cellulose (EC) on PU electrospun nanofibers in terms of morphological structures and drug release characteristics.