Spectral, analytical, thermal, and antimicrobial studies of novel sodium 2-[4(2-hydroxy-3-izopropylaminopropoxy)phenyl]acetamide (atenolol) dithiocarbamate and its divalent transition metal complexes

Goelcue A., Yavuz P.

RUSSIAN JOURNAL OF COORDINATION CHEMISTRY, cilt.34, sa.2, ss.106-114, 2008 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 34 Sayı: 2
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1134/s1070328408020061
  • Dergi Adı: RUSSIAN JOURNAL OF COORDINATION CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.106-114
  • İstanbul Teknik Üniversitesi Adresli: Hayır

Özet

Atenolol dithiocarbamate (ADTC) and its complexes with Cu(II), Co(II), Ni(II), Zn(II), and Cd(II) have been synthesized. These newly synthesized products have been characterized by elemental analyses (C, H. N, and S), thermal (thermogravimetry (TG) and differential thermal analyses (DTA)) as well as by spectral (UV, IR, and NMR (H-1)) studies. The stability constants (P) of metal complexes of ADTC have been determined by UV-Vis data in solutions in DMSO. The antimicrobial activities of the metal complexes have been screened in vitro against ten bacteria.