Spectral, analytical, thermal, and antimicrobial studies of novel sodium 2-[4(2-hydroxy-3-izopropylaminopropoxy)phenyl]acetamide (atenolol) dithiocarbamate and its divalent transition metal complexes


Goelcue A. , Yavuz P.

RUSSIAN JOURNAL OF COORDINATION CHEMISTRY, vol.34, no.2, pp.106-114, 2008 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 34 Issue: 2
  • Publication Date: 2008
  • Doi Number: 10.1134/s1070328408020061
  • Title of Journal : RUSSIAN JOURNAL OF COORDINATION CHEMISTRY
  • Page Numbers: pp.106-114

Abstract

Atenolol dithiocarbamate (ADTC) and its complexes with Cu(II), Co(II), Ni(II), Zn(II), and Cd(II) have been synthesized. These newly synthesized products have been characterized by elemental analyses (C, H. N, and S), thermal (thermogravimetry (TG) and differential thermal analyses (DTA)) as well as by spectral (UV, IR, and NMR (H-1)) studies. The stability constants (P) of metal complexes of ADTC have been determined by UV-Vis data in solutions in DMSO. The antimicrobial activities of the metal complexes have been screened in vitro against ten bacteria.