ADSORPTION AND RELEASE STUDIES OF TETRACYCLINE FROM A BIOACTIVE GLASS


Vanea E., Cavalu S., Banica F., Benyey Z., Göller G. , Simon V.

STUDIA UNIVERSITATIS BABES-BOLYAI CHEMIA, vol.56, no.3, pp.239-246, 2011 (Journal Indexed in SCI) identifier

  • Publication Type: Article / Article
  • Volume: 56 Issue: 3
  • Publication Date: 2011
  • Title of Journal : STUDIA UNIVERSITATIS BABES-BOLYAI CHEMIA
  • Page Numbers: pp.239-246

Abstract

This study aims to characterize a bioactive glass and to evaluate its ability to adsorb and release antimicrobial agents like tetracycline. Tetracycline adsorption and release were investigated using Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy and scanning electron microscopy. The amounts of withdrawn solution, after drug release, were analyzed by differential pulsed voltammetry and UV-Vis spectroscopy. The investigated glass system promotes an efficient response concerning the tetracycline loading and release in terms of drug delivery system for biomedical applications.