ADSORPTION AND RELEASE STUDIES OF TETRACYCLINE FROM A BIOACTIVE GLASS

Vanea E., Cavalu S., Banica F., Benyey Z., Göller G., Simon V.

STUDIA UNIVERSITATIS BABES-BOLYAI CHEMIA, cilt.56, sa.3, ss.239-246, 2011 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 56 Sayı: 3
  • Basım Tarihi: 2011
  • Dergi Adı: STUDIA UNIVERSITATIS BABES-BOLYAI CHEMIA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.239-246
  • İstanbul Teknik Üniversitesi Adresli: Evet

Özet

This study aims to characterize a bioactive glass and to evaluate its ability to adsorb and release antimicrobial agents like tetracycline. Tetracycline adsorption and release were investigated using Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy and scanning electron microscopy. The amounts of withdrawn solution, after drug release, were analyzed by differential pulsed voltammetry and UV-Vis spectroscopy. The investigated glass system promotes an efficient response concerning the tetracycline loading and release in terms of drug delivery system for biomedical applications.