Multi-channel seismic reflection profiles show that there is a thick northeast-southwest elongated lobe of uppermost Messinian and Pliocene-Quaternary sediments across the Cilicia Basin extending into the onland Adana Basin. Three prominent seismic markers divide this succession into three subunits. Detailed isopach maps constructed using a dense grid of depth-converted seismic reflection profiles show that these three subunits display distinctive sediment distribution patterns that can be confidently related to eastward deposition from the Goksu River to the west. Subsidence rates calculated at 95 locations within the Cilicia and Adana Basins using OSXBackstrip show that the central axis of the Cilicia-Adana Basin complex is subsiding at a rate of similar to 10-20 mm per year. The subsidence rates sharply decrease both toward the Misis-Kyrenia Fault zone in the south and east and the Turkish continental margin in the west and north to values of 0.10-0.15 mm per year. Subsidence rates were 0.10-0.20 mm per year during the deposition of the middle and upper Pliocene, but decreased to similar to 0.05 mm per year.