Microbubbles and nanobubbles have several characteristics that are comparable with millimeter- and centimeter-sized bubbles. These characteristics are their small size, which results in large surface area and high bioactivity, low rising velocity, decreased friction drag, high internal pressure, large gas dissolution capacity, negatively charged surface, and ability to be crushed and form free radicals. Controlling and modeling fundamental properties such as nucleation and of the dynamics of these bubbles is key to successfully exploiting their potential in the growing number of applications such as biomedical diagnosis and therapy, antimicrobial in aquaculture, environment, engineering, stock raising and marine industry. Laser-generated bubble dimensions can be characterized with an optical setup employing a high power continuous wave green laser for bubble generation. In this work, non-resonant, self-excited due to structurally nonlinear properties of the hydrogel, bubble formation was modeled as functions of well-controlled parameters of the colloidal media that is multi-layered and anisotropic, engineered uniquely. Copyright (C) 2021 The Authors.