Single-slice microwave imaging of breast cancer by reverse time migration


Bilgin E., Çayören M., Joof S., Cansiz G., Yilmaz T., Akduman İ.

MEDICAL PHYSICS, vol.49, no.10, pp.6599-6608, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 49 Issue: 10
  • Publication Date: 2022
  • Doi Number: 10.1002/mp.15917
  • Journal Name: MEDICAL PHYSICS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, INSPEC, MEDLINE
  • Page Numbers: pp.6599-6608
  • Keywords: breast cancer, electromagnetic imaging, microwave imaging, DIELECTRIC-PROPERTIES, ANTENNA-ARRAY, PHANTOMS, TISSUES, BAND
  • Istanbul Technical University Affiliated: Yes

Abstract

Purpose Microwave imaging of breast cancer is considered and a new microwave imaging prototype including the imaging algorithm, the antenna array, and the measurement configuration is presented. The prototype aims to project the geometrical features of the anomalies inside the breast to a single-slice image at the coronal plane depending on the complex dielectric permittivity variation among the tissues to aid the diagnosis . Methods The imaging prototype uses a solid cylindrical dielectric platform, where a total of 24 optimized Vivaldi antennas are embedded inside to form a uniform circular antenna array. The center of the platform is carved to create a hollow part for placement of the breast and the multistatic, microwave scattering parameters are collected with the antenna array around the hollow center. The dielectric platform further enhances the microwave impedance matching against the breast fat tissue and preserves the vertical polarization during the measurements. In the imaging phase, a computationally efficient inverse electromagnetic scattering method-reverse time migration (RTM)-is considered and adapted in terms of scattering parameters to comply with the actual measurements. Results The prototype system is experimentally tested against tissue-mimicking breast phantoms with realistic dielectric permittivity profiles. The reconstructed single-slice images accurately determined the locations and the geometrical extents of the tumor phantoms. These experiments not only verified the microwave imaging prototype but also provided the first experimental results of the imaging algorithm. Conclusions The presented prototype system implementing the RTM method is capable of reconstructing single-slice, nonanatomical images, where the hotspots correspond to the geometrical projections of the anomalies inside the breast.