c-Myc Inhibitor 10074-G5 Induces Murine and Human Hematopoietic Stem and Progenitor Cell Expansion and HDR Modulator Rad51 Expression

Aksoz M., Albayrak E., Aslan G. S. , Turan R. D. , Alyazici L. Y. , Siyah P., ...More

CURRENT CANCER DRUG TARGETS, vol.19, no.6, pp.479-494, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 6
  • Publication Date: 2019
  • Doi Number: 10.2174/1568009618666180905100608
  • Journal Name: CURRENT CANCER DRUG TARGETS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.479-494
  • Istanbul Technical University Affiliated: No

Abstract

Background: c-Myc plays a major role in the maintenance of glycolytic metabolism and hematopoietic stem cell (HSC) quiescence.