In this study, the procedure of using GIS for tracking the distribution of measles in a district of Istanbul was performed. The aim of the study is to present the available questionnaire data, which were collected during the measles epidemic, by means of maps. The designed maps show the relation and the distribution of individual cases on time and spatiality. A database is designed according to the questionnaires. Geo-spatial distribution of measles cases was analyzed. The obtained results were discussed and presented.