The use of novel photobleachable phthalocyanines to image DNA

Turanli-Yildiz B., SEZGIN T., Çakar Z. P., USLAN C., Sesalan B. Ş., GUL A.

SYNTHETIC METALS, vol.161, pp.1720-1724, 2011 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 161
  • Publication Date: 2011
  • Doi Number: 10.1016/j.synthmet.2011.06.012
  • Journal Name: SYNTHETIC METALS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1720-1724
  • Istanbul Technical University Affiliated: Yes


The interaction of cationic photobleachable cobalt 1 and palladium 2 phthalocyanines (pcs) with calf thymus (CT) DNA was investigated by UV/vis spectrophotometric methods and gel electrophoresis. With the addition of pcs, the change in the thermal denaturation profile of DNA was observed. The results indicated that these molecules exhibit efficient DNA binding activity. The new cationic cobalt derivative 1 was characterized by elemental analysis, UV, IR and mass spectrophotometry. (C) 2011 Elsevier B.V. All rights reserved.