Concrete construction, one of the oldest building practices, is commonly used in all parts of the world. Concrete is the primary building material for both residential and commercial constructions. The challenge of protecting the buildings, hence nation, against the attack of terrorism has raised the importance to explore the understanding of building materials against the explosion. In this research, a security check-post (reinforced concrete frame filled with plain cement concrete) has been chosen to study the behavior of structural elements under blast loading. Eight nitroglycerines-based dynamite blasts with varying amounts of explosive charge, up to 17 kg weight has been carried out at various scale distances. Pressure and acceleration time history records are measured using blast measuring instruments. Security check post after being exposed by explosive loading are photographed to view cracking/failure patterns on the structural elements. It is noted that with the increase of quantity of explosive, the dimensions of spalling and crack patterns increase on the front panels. Simple empirical analyses are conducted using ConWep and other design manuals such as UFC 3-340-02 (2008) and AASTP-1 (2010) for the purpose of comparison of blast parameters with the experimental records. The results of experimental workings are also compared with earlier researchers to check the compatibility of developed equations. It is believed that the current study presents the simple and preliminary procedure for calculating the air blast and ground shock parameters on the structures exposed to blast explosion.