Recent Point of Care (PoC) Electrochemical Testing Trends of New Diagnostics Platforms for Vitamin D


Kirazoğlu M., Benli B.

ChemistrySelect, cilt.8, sa.38, 2023 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 8 Sayı: 38
  • Basım Tarihi: 2023
  • Doi Numarası: 10.1002/slct.202301600
  • Dergi Adı: ChemistrySelect
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier
  • Anahtar Kelimeler: Electrochemical Sensor, Personal Nutrition, Smartphone, Vitamin D, Wearable Biosensors
  • İstanbul Teknik Üniversitesi Adresli: Evet

Özet

Recent advancements in electrochemical sensors for the detection of vitamins, particularly vitamin D, have drawn a lot of attention due to their outstanding advantages of simplicity and high sensitivity. For the purpose of detecting vitamin D in this circumstance, recent research has focused on developing electrochemical sensors. Although there is always space for improvement, electrochemical sensors for vitamin D detection and its transformation into point-of-care devices have made great strides lately. For example, the development of innovative electrode materials that can increase sensitivity and selectivity continues to garner a lot of interest. New suggestions on adsorptive detections using vitamin D carriers like nanoclays or hydroxyapatite-clay composites are being developed. These biosensors hold huge potential for the detection of cheap, disposable, and biodegradable solutions. Also, the biosensor could monitor the depletion of vitamin levels, providing a real-time platform for the Internet of Medical Things, fifth-generation wireless communications, and smartphone-based electrochemical sensors. Currently, electrochemical sensors based on smartphones have been proposed to detect using various biomarkers for monitoring several changes in glucose, etc. We believe smartphone-based electrochemical sensors and adsorptive sensing platforms provides a novel way toward point-of-care tests for identifying especially vitamin D deficiency and real-time monitoring.