Conversion of homochiral amines, beta-amino alcohols and alpha-amino acids to their chiral 2-substituted pyrrole derivatives


Demir A., AKHMEDOV I., SESENOGLU O., Alpturk O. , APAYDIN S., GERCEK Z., ...More

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, no.10, pp.1162-1167, 2001 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Publication Date: 2001
  • Doi Number: 10.1039/b008317h
  • Title of Journal : JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
  • Page Numbers: pp.1162-1167

Abstract

The conversion of the amino group of chiral amines, amino alcohols, amino acids and their esters into chiral 2-substituted pyrrole derivatives with various halogeno enones is described. The conversion works in good yield and without racemization. The synthesis of 2-phenylpyrrole derivatives was possible with amino alcohols but not with amino acids or their esters.