Conversion of homochiral amines, beta-amino alcohols and alpha-amino acids to their chiral 2-substituted pyrrole derivatives


Demir A., AKHMEDOV I., SESENOGLU O., Alpturk O. , APAYDIN S., GERCEK Z., ...Daha Fazla

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, ss.1162-1167, 2001 (SCI İndekslerine Giren Dergi) identifier identifier

  • Basım Tarihi: 2001
  • Doi Numarası: 10.1039/b008317h
  • Dergi Adı: JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
  • Sayfa Sayıları: ss.1162-1167

Özet

The conversion of the amino group of chiral amines, amino alcohols, amino acids and their esters into chiral 2-substituted pyrrole derivatives with various halogeno enones is described. The conversion works in good yield and without racemization. The synthesis of 2-phenylpyrrole derivatives was possible with amino alcohols but not with amino acids or their esters.