Some oil-based samples having oxygen, ester, amide, acid and/or hydroxyl structure were prepared for using as lubricants in PVC extrusion. After characterization studies, all samples were tested in PVC formulation using Brabender W50 EHT Lab-Station mixer and extruder. The results were compared with that of a commercial product. From the mixer results, it can be noted that energy consumption was lowered for samples containing acid and amide structures. Surface roughness and opacity of the products were improved when the extruder screw speed was increased from 20 rpm to 60 rpm.