It is necessary to be prepared for natural disasters, earthquakes in particular. In accordance with other efforts to this end, the Istanbul Metropolitan Municipality made further studies with the Japan International Cooperation Agency (JICA) in 2002 and prepared a report. However, difficulties experienced during daily accidents that necessitate quick responses, such as the putting out of fires and the transportation of the injured, indicate that even foreseen precautions are not easily put into practice. This article is prepared based on a Master's thesis entitled "Assessment on disaster management and emergency transportation routes in Istanbul." In the study, the present status of the city is evaluated, and a management model and recommendations related to transportation arrangements designed to best achieve emergency responses are presented.