A tale of too many centrosomes

Acilan C., Saunders W. S.

CELL, vol.134, no.4, pp.572-575, 2008 (SCI-Expanded) identifier

  • Publication Type: Article / Review
  • Volume: 134 Issue: 4
  • Publication Date: 2008
  • Doi Number: 10.1016/j.cell.2008.08.007
  • Journal Name: CELL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.572-575
  • Istanbul Technical University Affiliated: Yes

Abstract

Having the correct number of centrosomes is crucial for proper chromosome segregation during cell division and for the prevention of aneuploidy, a hallmark of many cancer cells. Several recent studies (Basto et al., 2008; Kwon et al., 2008; Yang et al., 2008) reveal the importance of mechanisms that protect against the consequences of harboring too many centrosomes.