The purpose of this research is to define the critical factors of technology transfer performance (TTP) and to measure its impact on quality performance (QP) and total quality management (TQM). In this study, a questionnaire form was designed and later conducted face to face with manufacturing managers or quality managers of the manufacturing firms in Turkey. Two hundred organizations of the largest 1000 companies according to the classification of Istanbul Chamber of Industry have been evaluated. A model was developed to investigate the relationships among technology transfer performance, quality performance, and total quality management that is based on theoretical considerations. Technology transfer performance has a positive and strong impact on total quality management, but it has no significant impact on quality performance. A positive and strong relationship was determined between total quality management and quality performance. The relationship between technology transfer performance and quality performance has become significant with the mediating role of total quality management. (C) 2016 The Authors. Published by Elsevier Ltd.