Cell Segmentation of 2D Phase-Contrast Microscopy Images with Deep Learning Method


Ayanzadeh A., Yagar H. O., YALÇIN ÖZUYSAL Ö., PESEN OKVUR D., Töreyin B. U., Unay D., ...Daha Fazla

Medical Technologies Congress (TIPTEKNO), İzmir, Türkiye, 3 - 05 Ekim 2019, ss.86-89 identifier identifier

  • Yayın Türü: Bildiri / Tam Metin Bildiri
  • Cilt numarası:
  • Doi Numarası: 10.1109/tiptekno.2019.8894978
  • Basıldığı Şehir: İzmir
  • Basıldığı Ülke: Türkiye
  • Sayfa Sayıları: ss.86-89
  • İstanbul Teknik Üniversitesi Adresli: Evet

Özet

The quantitative and qualitative ascertainment of cell culture is integral to the robust determination of the cell structure analysis. Microscopy cell analysis and the epithet structures of cells in cell cultures are momentous in the fields of the biological research process. In this paper, we addressed the problem of phase-contrast microscopy under cell segmentation application. In our proposed method, we utilized the state-of-the-art deep learning models trained on our proposed dataset. Due to the low number of annotated images, we propose a multi-resolution network which is based on the U-Net architecture. Moreover, we applied multi-combination augmentation to our dataset which has increased the performance of segmentation accuracy significantly. Experimental results suggest that the proposed model provides superior performance in comparison to traditional state-of-the-art segmentation algorithms.