Computational assessment of thermostability in miRNA:CNT system using molecular dynamics simulations


Güvensoy Morkoyun A. , Kurkcuoglu O.

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, vol.1865, no.2, 2021 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 1865 Issue: 2
  • Publication Date: 2021
  • Doi Number: 10.1016/j.bbagen.2020.129808
  • Title of Journal : BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Abstract

Background: Carbon nanotubes (CNTs) show great promise as theranostic agents due to their drug delivery properties, intrinsic near-infrared radiation-responsiveness, and magnetic functionalization. However, temperature elevation caused by these external stimuli during drug delivery should be considered for the evaluation of CNT-based systems loaded with temperature-sensitive biomolecules.