Computational assessment of thermostability in miRNA:CNT system using molecular dynamics simulations


Güvensoy Morkoyun A. , Kurkcuoglu O.

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, cilt.1865, sa.2, 2021 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 1865 Konu: 2
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1016/j.bbagen.2020.129808
  • Dergi Adı: BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Özet

Background: Carbon nanotubes (CNTs) show great promise as theranostic agents due to their drug delivery properties, intrinsic near-infrared radiation-responsiveness, and magnetic functionalization. However, temperature elevation caused by these external stimuli during drug delivery should be considered for the evaluation of CNT-based systems loaded with temperature-sensitive biomolecules.