The synthesis of pyrido(2,3,4-kl)acridine unit of some marine alkaloids


Ozturk T. , MCKILLOP A.

CANADIAN JOURNAL OF CHEMISTRY, cilt.78, ss.1158-1164, 2000 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 78 Konu: 9
  • Basım Tarihi: 2000
  • Doi Numarası: 10.1139/cjc-78-9-1158
  • Dergi Adı: CANADIAN JOURNAL OF CHEMISTRY
  • Sayfa Sayıları: ss.1158-1164

Özet

A simple and convenient synthesis of pyrido(2,3,4-kl)acridine (1), the main skeleton of some marine alkaloids, via cyclization and intramolecular nitrene insertion, is described. The importance of the planarity of the molecule during the nitrene insertion is explained.