The synthesis of pyrido(2,3,4-kl)acridine unit of some marine alkaloids

Ozturk T., MCKILLOP A.

CANADIAN JOURNAL OF CHEMISTRY, cilt.78, sa.9, ss.1158-1164, 2000 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 78 Sayı: 9
  • Basım Tarihi: 2000
  • Doi Numarası: 10.1139/cjc-78-9-1158
  • Dergi Adı: CANADIAN JOURNAL OF CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1158-1164
  • İstanbul Teknik Üniversitesi Adresli: Hayır

Özet

A simple and convenient synthesis of pyrido(2,3,4-kl)acridine (1), the main skeleton of some marine alkaloids, via cyclization and intramolecular nitrene insertion, is described. The importance of the planarity of the molecule during the nitrene insertion is explained.