Cefoperazone metal complexes and their antimicrobial investigations


Çinar M. E. , ERDOĞAN T., Gölcü A.

Journal of the Turkish Chemical Society, Section A: Chemistry, vol.8, no.2, pp.375-390, 2021 (Refereed Journals of Other Institutions) identifier

  • Publication Type: Article / Article
  • Volume: 8 Issue: 2
  • Publication Date: 2021
  • Doi Number: 10.18596/jotcssa.721414
  • Title of Journal : Journal of the Turkish Chemical Society, Section A: Chemistry
  • Page Numbers: pp.375-390
  • Keywords: Antimicrobial studies, Cefoperazone, Computation, Metal complexes

Abstract

© 2021, Turkish Chemical Society. All rights reserved.Transition metal (Cd(II), Co(II), Cu(II), Fe(III), Ni(II), Pd(II), Pt(II), Ru(III), Zn(II)) complexes of cefoperazone (CFP) were synthesized and their spectroscopic (IR, UV-Vis), magnetic, thermal (DTA-TG), and mass spectral investigations were conducted to characterize the metal-based complexes. Detailed insights into the electronic structures were provided by performing density functional theory (DFT) computations. Their antimicrobial studies were realized rendering their activities compared to that of the commercial cefoperazone.