EFFECTS OF A PORPHYRAZINE DERIVATIVE ON SOME DEVELOPMENTAL CHARACTERISTICS OF DROSOPHILA MELANOGASTER


Karatas A., Ertan F., Saki N., Baspinar E., Sevim A. M. , Gül A.

ACTA BIOLOGICA HUNGARICA, cilt.62, ss.426-440, 2011 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 62 Konu: 4
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1556/abiol.62.2011.4.8
  • Dergi Adı: ACTA BIOLOGICA HUNGARICA
  • Sayfa Sayıları: ss.426-440

Özet

In this study, the effects of a porphyrazine derivative, [octakis (2-trimethylammoniumethyl thio) porphy-razinatocobalt] octaiodide (CoPzq), were explored on the developmental characteristics, sex ratio and egg fertility of Drosophila melanogaster. CoPzq was preferred in the study due to its probability to be used as a chemotherapeutic agent in medicine. As a result of the application of CoPzq, a phenotypic abnormality was revealed within the individuals of F(1) and F(2) generation of Drosophila. Although individuals of F(2) generation did not directly come into contact with the chemical, the rate of abnormality is high. An increase was observed within both generations in terms of the egg fertility. Besides, a deviation emerged in the sex-ratio in some concentrations.