Natural alginate biopolymer montmorillonite clay composites for vitamin B2 delivery


KAYGUSUZ H., UYSAL M., Adımcılar V. , Erim F. B.

JOURNAL OF BIOACTIVE AND COMPATIBLE POLYMERS, vol.30, no.1, pp.48-56, 2015 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 30 Issue: 1
  • Publication Date: 2015
  • Doi Number: 10.1177/0883911514557014
  • Title of Journal : JOURNAL OF BIOACTIVE AND COMPATIBLE POLYMERS
  • Page Numbers: pp.48-56

Abstract

This work describes the in vitro release of a small drug, riboflavin, from novel calcium and barium crosslinked alginate-montmorillonite composite beads via oral route. Effect of crosslinking cation, concentration of montmorillonite and media on encapsulation efficiencies, and release profiles of riboflavin were studied. Beads were characterized using gravimetric swelling ability study, Fourier transform infrared spectroscopy, and scanning electron microscopy. Results indicate that addition of montmorillonite increases the encapsulation efficiencies and slows down the release rates significantly.