Synthesis and in vitro study of new highly boronated phthalocyanine

Shmal'ko, Ahmet; EFREMENKO, Anastasija; IGNATOVA, Anastasija; SIVAEV, Igor; FEOFANOV, Alexey; HAMURYUDAN, Esin; GUEL, Ahmet; KOVALENKO, Leonid; QI, Shicheng; BREGADZE, Vladimir

doi:10.1142/s1088424614500746

Synthesis and in vitro study of new highly boronated phthalocyanine

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Shmal'ko A., EFREMENKO A. V., IGNATOVA A. A., SIVAEV I. B., FEOFANOV A. V., HAMURYUDAN E., ...More

JOURNAL OF PORPHYRINS AND PHTHALOCYANINES, vol.18, pp.960-966, 2014 (SCI-Expanded)

Publication Type: Article / Article
Volume: 18
Publication Date: 2014
Doi Number: 10.1142/s1088424614500746
Journal Name: JOURNAL OF PORPHYRINS AND PHTHALOCYANINES
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.960-966
Istanbul Technical University Affiliated: Yes

Abstract

A new highly boronated Zn(II)-phthalocyanine with eight cobalt bis(dicarbollide) units (144 boron atoms) was prepared and its intracellular accumulation and distribution in GL6 human glioblastoma cells were studied. It was found that the boronated phthalocyanine undergoes strong aggregation in intracellular environment.