Synthesis and in vitro study of new highly boronated phthalocyanine


Shmal'ko A. , EFREMENKO A. V. , IGNATOVA A. A. , SIVAEV I. B. , FEOFANOV A. V. , HAMURYUDAN E. , ...Daha Fazla

JOURNAL OF PORPHYRINS AND PHTHALOCYANINES, cilt.18, ss.960-966, 2014 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 18
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1142/s1088424614500746
  • Dergi Adı: JOURNAL OF PORPHYRINS AND PHTHALOCYANINES
  • Sayfa Sayıları: ss.960-966

Özet

A new highly boronated Zn(II)-phthalocyanine with eight cobalt bis(dicarbollide) units (144 boron atoms) was prepared and its intracellular accumulation and distribution in GL6 human glioblastoma cells were studied. It was found that the boronated phthalocyanine undergoes strong aggregation in intracellular environment.