Diazoaldehyde chemistry .3. Synthesis of 4-acyl-1H-1,2,3-triazole derivatives

Sezer O., Dabak K., Akar A., Anac O.

HELVETICA CHIMICA ACTA, vol.79, no.2, pp.449-453, 1996 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 79 Issue: 2
  • Publication Date: 1996
  • Doi Number: 10.1002/hlca.19960790212
  • Journal Name: HELVETICA CHIMICA ACTA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.449-453
  • Istanbul Technical University Affiliated: Yes

Abstract

Ten new alpha-diazo-beta-oxoaldehydes were condensed with aniline, ammonia, hydroxylamine, and semicarbazide to yield new 4-acyl-(1-substituted)-1H-1,2,3-triazoles in moderate-to-good yields. The method is simple and regiospecific. The latter feature makes this method superior to the widely used acylacetylene + azide approach.