BMP-2 immobilized PCL/P3ANA Nanofibers for Bone Tissue Engineering

Guler Z., Sarac A. S.

E-Health And Bioengineering Conference (EHB), Iasi, Romanya, 19 - 21 Kasım 2015 identifier

  • Yayın Türü: Bildiri / Tam Metin Bildiri
  • Basıldığı Şehir: Iasi
  • Basıldığı Ülke: Romanya
  • İstanbul Teknik Üniversitesi Adresli: Evet

Özet

Poly (epsilon-caprolactone)/poly (m-anthranilic acid) (PCL/P3ANA) nanofibers were fabricated by electrospinning. Nanofibers were biofuctionalized with Bone morphogenic protein-2 (BMP-2) with 1-ethyl-3-(dimethyl-aminopropyl) carbodiimide hydrochloride (EDC)/N-hydroxyl succinimide (NHS) surface activation of carboxyl groups (-COOH) on PCL/P3ANA scaffold.