A SHORT NEW ROUTE TO THE PYRIDO[2,3,4-KL]ACRIDINE SUBUNIT COMMON TO PYRIDOACRIDINE ALKALOIDS OF MARINE ORIGIN

ALI, NM; CHATTOPADHYAY, SK; MCKILLOP, A; PERRETGENTIL, RM; OZTURK, Turan; REBELO, RA

doi:10.1039/c39920001453

A SHORT NEW ROUTE TO THE PYRIDO[2,3,4-KL]ACRIDINE SUBUNIT COMMON TO PYRIDOACRIDINE ALKALOIDS OF MARINE ORIGIN

Atıf İçin Kopyala

ALI N., CHATTOPADHYAY S., MCKILLOP A., PERRETGENTIL R., OZTURK T., REBELO R.

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, sa.19, ss.1453-1454, 1992 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Basım Tarihi: 1992
Doi Numarası: 10.1039/c39920001453
Dergi Adı: JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
Sayfa Sayıları: ss.1453-1454
İstanbul Teknik Üniversitesi Adresli: Hayır

Özet

A short new route to the pyrido[2,3,4-kl]acridine ring system has been developed from readily available quinoline precursors involving two key steps: (i) a palladium(O)-catalysed Suzuki cross-coupling reaction of 4-chloroquinolines with arylboronic acids, and (ii) an intramolecular nitrene insertion reaction of the nitrenes derived from 4-phenyl-5-azidoquinolines.