In this study, general characteristics of soils formed on different parent materials in three different regions of Nigde province, their relationship with lithological units and the extent to which they are suitable for agricultural purposes were determined. Physical and chemical analysis values of rock and soil samples were used to reveal the relationship between lithological units and soils formed in the study area and correlation analysis was applied among the parameters. Multi Criteria Decision Making method was used to determine the suitability of these soils which are formed depending on the parent materials for agricultural use. In order to determine the effect rates among the main criteria of soil, topography, climate and geology and their sub criteria, Analytical Hierarchy Process of Multi Criteria Decision Making method was applied. According to this; Depending on the influence of the lithological units, the soils developed around Bor district are of basic character and the soils developed in ciftlik and Golctik districts and their vicinity are more acidic reaction. In addition, it has been determined that the soils of the ciftlik district and its vicinity are developed by accumulation and in situ, while the soils around Golctik and Bor districts are developed in situ. In determining the suitability of soils for agricultural use, it was calculated that the main criteria of geology was 5.5% and the criteria of lithological units, which is the sub-criterion of this, was 2.7% effective.