Effect of oil extract from microalgae (Schizochytrium sp.) on the viability and apoptosis of human osteosarcoma cells.

Sahin D.

Current pharmaceutical biotechnology, vol.22, pp.1099-1105, 2021 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 22
  • Publication Date: 2021
  • Doi Number: 10.2174/1389201021666200928101029
  • Title of Journal : Current pharmaceutical biotechnology
  • Page Numbers: pp.1099-1105
  • Keywords: Natural products, osteosarcoma, polyunsaturated fatty acids, Schizochytrium sp., apoptosis, omega-3, POLYUNSATURATED FATTY-ACIDS, CANCER-CELLS, DOCOSAHEXAENOIC ACID, OMEGA-3-FATTY-ACIDS, PROLIFERATION, TUMOR, CYTOTOXICITY, EPA


Background: Osteosarcoma is a malignant tumor type that starts in bone and occurs most frequently in adolescents. Traditional techniques are insufficient, especially for metastatic ones. As alternative treatment techniques, natural products are worthy of examining due to being safe and innovative. Essential polyunsaturated fatty acids, mainly omega-3 and omega-6 fatty acids, have various positive effects on human health and growth. In addition, some PUFAs show anti-cancer activity by inducing apoptosis, specifically in cancer cells.