Effect of oil extract from microalgae (Schizochytrium sp.) on the viability and apoptosis of human osteosarcoma cells.

Sahin D.

Current pharmaceutical biotechnology, cilt.22, ss.1099-1105, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 22
  • Basım Tarihi: 2021
  • Doi Numarası: 10.2174/1389201021666200928101029
  • Dergi Adı: Current pharmaceutical biotechnology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, Biotechnology Research Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.1099-1105
  • Anahtar Kelimeler: Natural products, osteosarcoma, polyunsaturated fatty acids, Schizochytrium sp., apoptosis, omega-3, POLYUNSATURATED FATTY-ACIDS, CANCER-CELLS, DOCOSAHEXAENOIC ACID, OMEGA-3-FATTY-ACIDS, PROLIFERATION, TUMOR, CYTOTOXICITY, EPA
  • İstanbul Teknik Üniversitesi Adresli: Evet

Özet

Background: Osteosarcoma is a malignant tumor type that starts in bone and occurs most frequently in adolescents. Traditional techniques are insufficient, especially for metastatic ones. As alternative treatment techniques, natural products are worthy of examining due to being safe and innovative. Essential polyunsaturated fatty acids, mainly omega-3 and omega-6 fatty acids, have various positive effects on human health and growth. In addition, some PUFAs show anti-cancer activity by inducing apoptosis, specifically in cancer cells.