A fast regularized least-squares method for retinal vascular oxygen tension estimation using a phosphorescence lifetime imaging model

Gunay G., Yıldırım İ.

BIOMEDICAL ENGINEERING ONLINE, vol.12, 2013 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 12
  • Publication Date: 2013
  • Doi Number: 10.1186/1475-925x-12-106
  • Journal Name: BIOMEDICAL ENGINEERING ONLINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Istanbul Technical University Affiliated: Yes

Abstract

Background: Monitoring retinal oxygenation is of primary importance in detecting the presence of some common eye diseases. To improve the estimation of oxygen tension in retinal vessels, regularized least-squares (RLS) method was shown to be very effective compared with the conventional least-squares (LS) estimation. In this study, we propose an accelerated RLS estimation method for the problem of assessing the oxygenation of retinal vessels from phosphorescence lifetime images.