Cenozoic in midwest and central Anatolia presents various of mineral deposits. Following the Laramien orogeny, formations including the conglomerate, marl, clay and limestone constitute a gradual transition from marine to terrestrial facies. Volcanic tuffs are sometimes observed in this lithological unit. All this sedimentary sequence are generally cut by andesite, dacite and to a lesser extent basalt which were most commonly altered. Zeolites are developed depending on the hydrothermal alteration of volcanic rocks. Berate constitutes the richest ore deposit of Turkey and world. Salt, thenardite, celestite, trona and iron deposits with minor quantities are also important ore deposits for defined Cenozoic sequence in Anatolia compared to berates. The biggest brown coal formations of Turkey are also found in this Cenozoic sequence. Some separate barite occurrences in volcanic origin can be included in this sequence as the mineral potential of Turkey.