Biological Particle Manipulation: An Example of Jurkat Enrichment


Altinagac E., Ozcan S. S. , Genc Y., Kizil H. , Trabzon L.

IEEE 10th International Conference on Nano/Micro Engineered and Molecular Systems (NEMS), Xian, China, 7 - 11 April 2015, pp.25-27 identifier

  • Publication Type: Conference Paper / Full Text
  • City: Xian
  • Country: China
  • Page Numbers: pp.25-27

Abstract

Separation of microparticles and living cells are studied with computational and experimental methods. The flow behaviors of particles are modeled and simulated using COMSOL Multiphysics 4.3a software. Lab-on-a-chip devices having a Ti interdigitated electrode layer on a glass substrate and a PDMS microchannel are fabricated to investigate the most effective design for separating particles based on their sizes. Polystyrene particles in different diameters (3.2 mu m and 9.8 mu m) are used in our experiments and experiments with T-lymphocytes and B lymphoblasts are in progress.