Effect of Ficus carica leaf extract on the gene expression of selected factors in HaCaT cells

Turkoglu M. , Pekmezci E., Kilic S., Dundar C., Sevinc H.

JOURNAL OF COSMETIC DERMATOLOGY, vol.16, no.4, 2017 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 16 Issue: 4
  • Publication Date: 2017
  • Doi Number: 10.1111/jocd.12344
  • Title of Journal : JOURNAL OF COSMETIC DERMATOLOGY
  • Keywords: Ficus carica, HaCaT, VEGF, TNF-alpha, IL-1 alpha, SRD5A2, ENDOTHELIAL GROWTH-FACTOR, TUMOR-NECROSIS-FACTOR, HAIR FOLLICLE GROWTH, IN-VITRO, ANTIOXIDANT ACTIVITY, CYTOKINE PROFILES, ALOPECIA-AREATA, FACTOR-ALPHA, PATHOGENESIS, SKIN

Abstract

BackgroundFicus carica Linn. (Fc), common fig, has been traditionally used for many metabolic, cardiovasculary, respiratory, gastrointestinal, and skin disorders. Several studies were performed showing its anti-inflammatory, anti-angiogenic, anticancerogenic, and tissue-protective effects. In all of those studies, the positive effects of Fc were concluded as the result of its antioxidant and anti-inflammatory features due to the polyphenols it contains.