Effect of Ficus carica leaf extract on the gene expression of selected factors in HaCaT cells

Turkoglu M., Pekmezci E., Kilic S., Dundar C., Sevinc H.

JOURNAL OF COSMETIC DERMATOLOGY, vol.16, no.4, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 16 Issue: 4
  • Publication Date: 2017
  • Doi Number: 10.1111/jocd.12344
  • Journal Name: JOURNAL OF COSMETIC DERMATOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: Ficus carica, HaCaT, VEGF, TNF-alpha, IL-1 alpha, SRD5A2, ENDOTHELIAL GROWTH-FACTOR, TUMOR-NECROSIS-FACTOR, HAIR FOLLICLE GROWTH, IN-VITRO, ANTIOXIDANT ACTIVITY, CYTOKINE PROFILES, ALOPECIA-AREATA, FACTOR-ALPHA, PATHOGENESIS, SKIN
  • Istanbul Technical University Affiliated: Yes

Abstract

BackgroundFicus carica Linn. (Fc), common fig, has been traditionally used for many metabolic, cardiovasculary, respiratory, gastrointestinal, and skin disorders. Several studies were performed showing its anti-inflammatory, anti-angiogenic, anticancerogenic, and tissue-protective effects. In all of those studies, the positive effects of Fc were concluded as the result of its antioxidant and anti-inflammatory features due to the polyphenols it contains.