Effect of some antidepressants on glycaemia and insulin levels of normoglycaemic and alloxan-induced hyperglycaemic mice

Erenmemisoglu A., Ozdogan U., Saraymen R., Tutus A.

JOURNAL OF PHARMACY AND PHARMACOLOGY, cilt.51, sa.6, ss.741-743, 1999 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 51 Sayı: 6
  • Basım Tarihi: 1999
  • Doi Numarası: 10.1211/0022357991772899
  • Dergi Adı: JOURNAL OF PHARMACY AND PHARMACOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.741-743
  • İstanbul Teknik Üniversitesi Adresli: Hayır

Özet

Depression is an important problem among diabetic patients. We have investigated the effect of some antidepressant drugs on plasma glucose and insulin levels in normoglycaemic and alloxan-induced diabetic mice. For this purpose the effects of nortryptiline (as an example of a tricyclic antidepressant) and fluoxetine and sertraline (as examples of selective 5-HT re-uptake inhibitors) were examined on plasma glucose and insulin levels.