In the current study, exceptional and reasonable heterogeneous ZnO/PVP nanocatalysts were synthesized via the chemical reduction method followed by ultra-sonication for methyl orange degradation in the aqueous medium. The synthesized nanocatalysts were confirmed using different characterization techniques such as Energy Dispersive X-ray, Scanning Electron Microscope, X-ray diffraction analysis, Zeta Potential, Dynamic light Scattering, UV-Visible spectroscopy, and Fourier Transform Infrared Spectroscopy. To validate the competency of the nanocatalysts as the photocatalyst, the synthesized ZnO/PVP nanocatalysts were applied to the degradation of methyl orange dye. Lastly, the fabricated catalyst demonstrated splendid catalytic efficiency; within 90 seconds, more than 98% degradation of methyl orange dye was perceived using 150 ??g nanocatalysts dose in the aqueous medium. The fabricated ZnO/PVP nanocatalysts illustrate many benefits above traditional routes for degrading the toxic and hazardous dye, like a short time, high percentile of degradation, the least amount of nanocatalysts, and admirable reusability. On the above facts, it is recommended that these viable and effective nanocatalysts can be applied successfully on the commercial level for degradation hazard pollutants.