Effects of Electrospinning Parameters on Gelatin/Poly(epsilon-Caprolactone) Nanofiber Diameter


Gonen S. O. , TAYGUN M. E. , KUCUKBAYRAK S.

CHEMICAL ENGINEERING & TECHNOLOGY, cilt.38, ss.844-850, 2015 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 38 Konu: 5
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1002/ceat.201400323
  • Dergi Adı: CHEMICAL ENGINEERING & TECHNOLOGY
  • Sayfa Sayıları: ss.844-850

Özet

An electrospinning procedure was carried out to fabricate gelatin/poly(epsilon-caprolactone) (Gt/PCL) nanofibers. Response surface methodology based on a three-level, four-variable Box-Behnken design technique was used to model the resultant diameter of the as-spun nanofibers. A second-order model was obtained to describe the relationship between the fiber diameter and the electrospinning parameters, namely Gt concentration, PCL concentration, content of acetic acid in the overall solvent, and content of Gt solution in the blend solution. The individual and the interactive effects of these parameters on the fiber diameter were determined. Validation experiments verified the accuracy of the model which provided a simple and effective method for fabricating nanofibers with a controllable and predictable fiber diameter.