Evolutionary Engineering of Yeast

Alkim, Ceren; Turanli-Yildiz, Burcu; Çakar, Zeynep

doi:10.1007/978-1-4939-0563-8_10

Evolutionary Engineering of Yeast

Atıf İçin Kopyala

Alkim C., Turanli-Yildiz B., Çakar Z. P.

YEAST METABOLIC ENGINEERING: METHODS AND PROTOCOLS, cilt.1152, ss.169-183, 2014 (Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 1152
Basım Tarihi: 2014
Doi Numarası: 10.1007/978-1-4939-0563-8_10
Dergi Adı: YEAST METABOLIC ENGINEERING: METHODS AND PROTOCOLS
Derginin Tarandığı İndeksler: Scopus
Sayfa Sayıları: ss.169-183
İstanbul Teknik Üniversitesi Adresli: Evet

Özet

Evolutionary engineering is an inverse metabolic engineering strategy which is based on increasing genetic diversity and screening large populations for desired phenotypes. This strategy is highly advantageous in certain situations over rational metabolic engineering approaches, since there is little or no requirement of detailed genetic background information for the trait of interest. Here, we describe the experimental methodology for selecting stress-resistant yeast strains via evolutionary engineering approach by either serial batch or chemostat cultivations.