Dual Release Carriers for Cochlear Delivery


Rahmani S., ROSS A. M. , Park T., Durmaz H. , Dishman A. F. , Prieskorn D. M. , ...More

ADVANCED HEALTHCARE MATERIALS, vol.5, no.1, pp.94-101, 2016 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 5 Issue: 1
  • Publication Date: 2016
  • Doi Number: 10.1002/adhm.201500141
  • Title of Journal : ADVANCED HEALTHCARE MATERIALS
  • Page Numbers: pp.94-101

Abstract

The fabrication of a carrier system capable of selectively encapsulating two therapeutics, piribedil and glial cell derived neurotrophic factor, in select compartments, and the programming of their independent release rates is investigated. The characterization of these particles, the release of each therapeutic, and the persistence of the particles within Guinea pig cochlea are assessed.