The synthesized Ce-doped ZnS nanoparticles by chemical precipitation method were dropped on TiO2 coated on FTO conductive glass substrates. The photovoltaic property of the obtained Ce-doped ZnS/TiO2/FTO structure was investigated by measuring current density (J) voltage (V) and incident photon to current efficiency (IPCE), respectively. Power conversion efficiency of nanoparticles was calculated using the recorded J-V curve. Thus, both IPCE and J-V measurements have been shown experimentally that Ce-doped ZnS nanoparticles can be used as promising sensitizers in photovoltaic applications. Morever, the structural, elemental and photovoltaic properties of Ce-doped nanoparticles were studied by x-ray diffraction (XRD), energy dispersive x-ray (EDX), optical absorption and photoluminescence (PL) measurements, respectively. The characterization results were discussed.