Comparative determination of the cardioselectivity of taxine and verapamil in the isolated aorta, atrium and jejunum preparations of rabbits

Tekol Y., Gogusten B.

ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH, vol.49, no.8, pp.673-678, 1999 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 49 Issue: 8
  • Publication Date: 1999
  • Doi Number: 10.1055/s-0031-1300481
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.673-678
  • Istanbul Technical University Affiliated: No


The calcium channel antagonistic effect of taxine: (CAS 12607-93-1) (active principle of leaves of English yew; Taxus baccata L.) was investigated in isolated aorta of rabbit, and its organ selectivity was determined and compared with that of verapamil (CAS 52-53-9) in isolated aorta. atrium and jejunum preparations of rabbits.