Comparative determination of the cardioselectivity of taxine and verapamil in the isolated aorta, atrium and jejunum preparations of rabbits

Tekol Y., Gogusten B.

ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH, cilt.49, sa.8, ss.673-678, 1999 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 49 Konu: 8
  • Basım Tarihi: 1999
  • Doi Numarası: 10.1055/s-0031-1300481
  • Sayfa Sayıları: ss.673-678


The calcium channel antagonistic effect of taxine: (CAS 12607-93-1) (active principle of leaves of English yew; Taxus baccata L.) was investigated in isolated aorta of rabbit, and its organ selectivity was determined and compared with that of verapamil (CAS 52-53-9) in isolated aorta. atrium and jejunum preparations of rabbits.