Facile Syntheses of 3-Hydroxyflavones

Gunduz S., GOREN A. C., Ozturk T.

ORGANIC LETTERS, vol.14, no.6, pp.1576-1579, 2012 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 14 Issue: 6
  • Publication Date: 2012
  • Doi Number: 10.1021/ol300310e
  • Journal Name: ORGANIC LETTERS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1576-1579
  • Istanbul Technical University Affiliated: No


Modification of the present synthetic methods led to the syntheses of 3-hydroxyflavones in a shorter reaction time, with simple purification and higher yields. Application of the method provided the syntheses of 3HFs having a hydroxyl group on the phenyl ring (ring B) in one step, which is an improvement compared to the four steps, long reaction time, and low yield using the current method available in the literature.