This study describes the coeval development of the depositional environments in three areas across the Mut Basin (Southern Turkey) throughout the Late Burdigalian (early Miocene). Antecedent topography and rapid high-amplitude sea-level change are the main controlling factors on stratigraphic architecture and sediment type. Stratigraphic evidence is observed for two high-amplitude (100-150 m) sea-level cycles in the Late Burdigalian to Langhian. These cycles are interpreted to be eustatic in nature and driven by the long-term 400-Ka orbital eccentricity-cycle-changing ice volumes in the nascent Antarctic icecap. We propose that the Mut Basin is an exemplary case study area for guiding lithostratigraphic predictions in early Miocene shallow-marine carbonate and mixed environments elsewhere in the world.