Determination of Serotonin-Norepinephrine Reuptake Inhibitor Antidepressants in Pharmaceuticals and Biological Material

Saka C., Sahin Ö.

CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY, cilt.43, sa.1, ss.2-34, 2013 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 43 Sayı: 1
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1080/10408347.2011.645377
  • Dergi Adı: CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2-34
  • Anahtar Kelimeler: antidepressant, serotonin-norepinephrine reuptake inhibitors, analytical methods, pharmaceutical and biological samples, PERFORMANCE LIQUID-CHROMATOGRAPHY, TANDEM MASS-SPECTROMETRY, SOLID-PHASE EXTRACTION, SIMULTANEOUS STEREOSELECTIVE ANALYSIS, O-DESMETHYLVENLAFAXINE ENANTIOMERS, NEW-GENERATION ANTIDEPRESSANTS, SILICA STATIONARY-PHASE, N-DESMETHYL-METABOLITES, INDICATING HPTLC METHOD, HPLC METHOD DEVELOPMENT
  • İstanbul Teknik Üniversitesi Adresli: Hayır

Özet

Serotonin-norepinephrine reuptake inhibitors (SNRIs) are a newer form of antidepressant drugs. SNRIs include desvenlafaxine, duloxetine, milnacipran, venlafaxine, and sibutramine. The present study covers the analytical research on SNRIs and their main metabolites, focusing on bioanalytical and pharmaceutical applications. These analytical methods are generally chromatographic, electroanalytical, spectrometric, and electrophoretic methods.