Apium Plants: Beyond Simple Food and Phytopharmacological Applications


Salehi B., Venditti A., Frezza C., YÜCETEPE A., Altuntaş Ü. , ULUATA S., ...More

APPLIED SCIENCES-BASEL, vol.9, no.17, 2019 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Review
  • Volume: 9 Issue: 17
  • Publication Date: 2019
  • Doi Number: 10.3390/app9173547
  • Title of Journal : APPLIED SCIENCES-BASEL
  • Keywords: Apium, botany, medicinal use, phytochemicals, pharmacological properties, FRESH-CUT CELERY, INDUCED REPRODUCTIVE TOXICITY, GRAVEOLENS-VAR. DULCE, REPENS JACQ. LAG., CELL-CYCLE ARREST, CHEMICAL-COMPOSITION, ESSENTIAL OILS, LISTERIA-MONOCYTOGENES, HEPATOPROTECTIVE ACTIVITY, ANTIOXIDANT ACTIVITIES

Abstract

Apium plants belong to the Apiaceae family and are included among plants that have been in use in traditional medicine for thousands of years worldwide, including in the Mediterranean, as well as the tropical and subtropical regions of Asia and Africa. Some highlighted medical benefits include prevention of coronary and vascular diseases. Their phytochemical constituents consist of bergapten, flavonoids, glycosides, furanocoumarins, furocoumarin, limonene, psoralen, xanthotoxin, and selinene. Some of their pharmacological properties include anticancer, antioxidant, antimicrobial, antifungal, nematocidal, anti-rheumatism, antiasthma, anti-bronchitis, hepatoprotective, appetizer, anticonvulsant, antispasmodic, breast milk inducer, anti-jaundice, antihypertensive, anti-dysmenorrhea, prevention of cardiovascular diseases, and spermatogenesis induction. The present review summarizes data on ecology, botany, cultivation, habitat, medicinal use, phytochemical composition, preclinical and clinical pharmacological efficacy of Apium plants and provides future direction on how to take full advantage of Apium plants for the optimal benefit to mankind.