Reactions of Quino-Ketenes with C-Nucleophiles: Syntheses of (2-Hydroxyphenyl)methanols and 2-Hydroxyphenyl Ketones

Gunduz H., Kumbaraci V., Talinli N.

HELVETICA CHIMICA ACTA, vol.97, no.8, pp.1097-1106, 2014 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 97 Issue: 8
  • Publication Date: 2014
  • Doi Number: 10.1002/hlca.201300391
  • Journal Name: HELVETICA CHIMICA ACTA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1097-1106
  • Istanbul Technical University Affiliated: Yes

Abstract

In this study, we have developed a new, efficient, and one-step protocol for the synthesis of derivatives of 2,4-dihydroxyphenyl ketones and/or 2,4-dihydroxyphenyl/naphthalenyl methanols starting from benzodioxinones/naphthodioxinones and organolithium compounds. Reactions have been performed under thermal conditions without catalyst. This work is the first example of the preparation of these products starting from 2-hydroxy acids.