One of the most promising technologies to enhance the quality of life of quadriplegia patients is smart home environments. Security has a paramount importance for all health information systems, but it is generally overlooked until a major security breach occurs. Especially in an application specifically targeting people with disabilities, ignoring security might have dire consequences therefore we think that proactive measures should be taken by system designers. In this paper, we present SHA, a secure voice activated smart home for quadriplegia patients. The principal contribution of our system lies behind the security mechanisms incorporated in the proposed smart home architecture which has an integrated framework including ambient assistance and remote health monitoring.