Impact behavior of sandwich panels with auxetic and hexagonal honeycomb cores are investigated experimentally and numerically. Re-entrant and antitetrachiral geometries are considered for auxetic cores. In the experimental side of the study, auxetic and honeycomb cores are produced using a 3D printer. The sandwich panels are then produced by attaching aluminium face sheets and cores. The impact tests are performed using a particle impact test system. The numerical analyses are achieved by using LSDYNA finite element software. The deformation results are compared and the effect of having different type of core is evaluated.