We document Quaternary fluvial incision driven by fault-controlled surface deformation in the inverted intermontane Gok rmak Basin in the Central Pontide mountains along the northern margin of the Central Anatolian Plateau. In-situ-produced Be-10, Ne-21, and Cl-36 concentrations from gravel-covered fluvial terraces and pediment surfaces along the trunk stream of the basin (the Gok rmak River) yield model exposure ages ranging from 71ka to 34645ka and average fluvial incision rates over the past similar to 350ka of 0.280.01mm a(-1). Similarities between river incision rates and coastal uplift rates at the Black Sea coast suggest that regional uplift is responsible for the river incision. Model exposure ages of deformed pediment surfaces along tributaries of the trunk stream range from 605ka to 110 +/- 10ka, demonstrating that the thrust faults responsible for pediment deformation were active after those times and were likely active earlier as well as explaining the topographic relief of the region. Together, our data demonstrate cumulative incision that is linked to active internal shortening and uplift of similar to 0.3mm a(-1) in the Central Pontide orogenic wedge, which may ultimately contribute to the lateral growth of the northern Anatolian Plateau.